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Unleash the power of arrayed CRISPR screening!
This arrayed synthetic crRNA library targeting nearly 8000 human genes for CRISPR-Cas9 gene knockdown screens is now available.
A workflow for CRISPR-Cas9 high throughput arrayed screening with synthetic crRNA
On-demand version now available
Free print edition now available
From single gene analysis to genome-scale screens, find your Gene Editing, RNAi, and Gene Expression solutions in the newly updated Dharmacon product guide!
CRISPR-Cas9 Gene Editing
Simplify your gene editing workflow with the Edit-R CRISPR-Cas9 platform. Custom or predesigned ready-to-use DNA and synthetic RNA reagents enable you to quickly assess multiple target sites per gene across one or hundreds of genes – moving you closer to high-confidence results.
Custom siRNA screening libraries for ANY species
Enjoy algorithm-designed siRNA produced with a novel enzymatic method to support large functional genomics studies in non-human or mouse models. Whether you only want to screen 1000 key gene targets or a whole genome, we now have a solution for you!
Our RNAi products encompass the most complete portfolio of innovative tools for transient, long-term, inducible and in vivo RNAi applications.
Interrogate gene function through targeted genome editing using powerful molecular tools to permanently alter endogenous gene expression.
cDNAs and ORFs can be used to overexpress particular genes of interest. Choose from individual clones, lentiviral ORFs, and genome-scale libraries.
Design, order, and learn more about custom siRNA, single-stranded RNA, and microRNA products. Use our free, online siRNA design tool or specify your own sequences.
A comprehensive portfolio of competitively priced, proven transfection reagents for a wide range of applications.
The safest and most effective strategy for packaging virus to efficiently express your shRNA or gene of interest.
A quick list of points to address when planning a gene knockout experiment with CRISPR-Cas9
DharmaFECT kb enables highly efficient DNA delivery into most cell types with minimal cytotoxicity.
With so many to choose from—how do you know which Cas9 is best for your experiment?
An overview of a July 2016 publication on the versatility of synthetic guide RNA in CRISPR-Cas9 gene editing.