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    Edit-R CRISPR-Cas9 Genome Engineering

    Optimized tools for high-confidence gene editing

    The Dharmacon Edit-R CRISPR-Cas9 platform provides predesigned, ready-to-use DNA and RNA components to enable rapid and highly functional gene editing experiments.

    • Higher assurance of functional knockout from predesigned genomewide guide RNAs
    • Improve Cas9 nuclease expression by choosing the optimal promoter for your cell type
    • High-quality synthetic and lentiviral reagents to meet every experimental need
    • Licensed from the Broad Institute as provider of CRISPR reagents for research use

    Edit-R CRISPR-Cas9 Genome Engineering Products

    Synthetic Guide RNA

    • Edit-R predesigned crRNA

      Algorithm-optimized crRNA for genome-wide coverage of human, mouse, or rat genes. Modifications for nuclease resistance improve DNA-free editing. Simply search for your gene!

    • Edit-R tracrRNA

      Edit-R trans-activating CRISPR RNA (tracrRNA) is synthetic, HPLC-purified, long RNA required for use with Edit-R crRNA to form the complex that programs Cas9 nuclease. It is modified for nuclease resistance and can be used with modified or unmodified Edit-R crRNA.

    • Edit-R Synthetic Positive crRNA Controls and Detection Primers

      Species-specific crRNAs targeting well-characterized genes, as well as mismatch detection assay primers, to determine the effectiveness of your gene editing conditions for maximal efficiency.

    • Edit-R Synthetic crRNA Non-targeting Controls

      Non-targeting controls to evaluate cellular responses to CRISPR-Cas9 components in the absence of gene target-specific crRNA.

    • Edit-R crRNA Libraries

      Pre-defined collections of popular gene families and pathways for high-throughput applications.

    • Cherry-pick libraries

      Have a favorite gene list? Customize and order plates of predesigned crRNA for knockout studies in your targets of interest.

    Lentiviral Guide RNA

    Vector-based Cas9 Nuclease

    DNA-free Cas9 Nuclease

    Custom Guide RNA Design & Ordering Tools

    • CRISPR RNA Configurator

      Place a custom gRNA order, or design and order your own crRNA or lentiviral sgRNA with our easy-to-use interface.

    HDR Donor Template Design & Ordering Tools

    HDR Donor Template Kits

    Applications

    Resources

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