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Services

Enable new experimental possibilities with Custom RNA synthesis

No pre-designed product to fit your needs? Use our online design tools and extensive synthesis options to create custom products specific to your application.

Dharmacon custom RNA synthesis enables additional experimental abilities and scientific discoveries through unique chemistry, high quality, and dependable customer services.

  • Benefits of 2'-ACE synthesis chemistry
  • Extensive chemical modification options for RNA synthesis
  • Long, high yield single-stranded RNA
  • High performance siRNA with proprietary modifications
  • "Have it your way" with post synthesis options
  • siDESIGN Center

    The siDESIGN Center is a free online design tool that offers the power of the Dharmacon SMARTselection algorithm for the custom design of highly functional siRNAs.

  • CRISPR RNA Configurator

    The tools in the CRISPR RNA Configurator allow you to quickly and easily generate guide RNA sequences for ordering, either as synthetic crRNA or lentiviral sgRNA.

  • Edit-R HDR Donor Designer

    Quickly and easily design and order a donor template for precise CRISPR-Cas9 gene editing. Custom-synthesized ssDNA donor oligonucleotide (oligo) templates for precise insertion, removal, or replacement of genomic DNA can be rapidly designed and ordered with this powerful online tool.

Custom Libraries

  • Cherry-pick Library Plater

    Enjoy fast and easy online ordering - no quote required. Cherry-pick from our algorithm-optimized, predesigned products lines of siRNA, microRNA, and crRNA reagents to build your own custom library.

  • Custom Lentiviral Pools

    Build your own Custom lentiviral pools by selecting the product format desired, any available human, mouse, or rat constructs, and determining the number of genes per pool, as well as, the number of shRNAs per gene target.

  • Zoonome siRNA Libraries

    Developed for the purpose of supporting veterinary, agricultural, and other research working in non-human or mouse models, Zoonome siRNA Libraries are custom collections of algorithm-designed siRNAs produced with a novel enzymatic method to support large functional genomics studies in nearly any species.

Custom siRNA Syntheis

  • Order siRNA

    Easy online ordering of standard, Dharmacon enhanced, and modified siRNAs. Ability to incorporate mismatches and internal modifications except for positions where restricted by Dharmacon patented modifications do not allow for changes in base content.

  • SMARTpool Design & Synthesis

    To complement our pre-designed siRNA collections and support a broad range of RNAi experiments, our siRNA design experts can provide custom SMARTpool reagents targeting genes outside of our genomewide offerings, like specific isoforms and splice variants or alternative species.

Custom DNA

  • Order Single-strand DNA

    Use our simple online ordering tool to design and purchase custom oligos containing only deoxy-bases (A,C,T,G). Include various modifications, processing methods, and synthesis scales.

  • Order Multiple Single-strand DNAs

    Order multiple DNA only oligos with same design criteria in one convenient interface. With this tool simply enter your sequences and select criteria that will apply to all DNA oligos.

Custom RNA

  • Order Single-strand RNA

    Use our custom RNA tool to create and order RNA and RNA-DNA hybrid molecules with a wide variety of synthesis scales, chemical modifications, dye labels and purification options.

  • Order Multiple Single-strand RNAs

    Order multiple RNA and RNA-DNA hybrid oligos with same design criteria in one convenient interface. With this tool simply enter your sequences and select criteria that will apply to all oligos.

Custom microRNA Modulation Tools

Modify an existing microRNA mimic or inhibitor, target a novel microRNA, or request an Accell microRNA Inhibitor or Stabilized Mimic for special applications.

Preclinical and OEM RNA & DNA synthesis

Quality custom oligonucleotides for research and preclinical applications. Our preclinical/OEM manufacturing service provides academic and industry partners with an ISO 9001-certified facility, cost-effective and timely oligonucleotide materials for novel research (in vitro) thru preclinical use (in vivo).

Request Pricing

  • Custom Lentiviral Pools

    Build your own Custom lentiviral pools by selecting the product format desired, any available human, mouse, or rat constructs, and determining the number of genes per pool, as well as, the number of shRNAs per gene target.

  • shRNA Arrayed Libraries

    For custom arrayed shRNA clone libraries, please note that we will need to contact you for your list of desired genes before an accurate quote can be issued. Pricing and ordering for individual shRNA clones are available on our web pages and do not require a pricing request.

  • siRNA or crRNA Libraries

    Custom libraries may be configured, priced, and ordered online with the Cherry-pick Library Plater. Use this form to request a quote for either a predefined catalog library or a custom collection.

  • cDNA and ORF Clone Libraries

    For custom arrayed cDNA and ORF clone libraries, please note that we will need to contact you for your list of desired genes before an accurate quote can be issued. Pricing and ordering for individual cDNA and ORF clones are available on our web pages and do not require a quote request.

  • microRNA Library

    Custom collections of microRNA reagents may be configured, priced, and ordered online with the Cherry-pick Library Plater. If you are unable to place online orders, you may use this form to request a quote.

  • Custom RNA/DNA Synthesis

    Please review questions on the pricing request form and provide required information to receive a pricing quote for Custom RNA Synthesis.

  • Custom microRNA Synthesis

    Please review questions on the pricing request form and provide required information to receive a pricing quote for Custom microRNA Synthesis.

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